When Locke appeared next to Hurley's table outside the Institute, Hurley thought Locke was dead and his spirit came to visit him like Charlie had done. He called out to Nurse Lazenby to ask if he was speaking to an old man in a wheelchair and she confirmed this. When Hurley started acting up and wanted to get away from Locke after learning he was with Abaddon, the nurse and another orderly escorted Hurley back inside the Institute. ("The Life and Death of Jeremy Bentham")
An unspecified amount of time later, Nurse Lazenby was still working at Santa Rosa. Ben Linus asked her if could see a patient by the name of Keith Johnson, who turned out to be Walt. ("The New Man in Charge")
- She was credited differently in the press release each time she appeared. She was credited simply as a nurse in "Dave", and as an orderly in "The Beginning of the End". Later, she was credited as Susie in "The Life and Death of Jeremy Bentham", and was uncredited in "The New Man in Charge".
- Nurse Lazenby's family name was revealed when Hurley spoke to her in "Dave". Her first name was not given until "The Life and Death of Jeremy Bentham".
- Beside playing the role of Susie, actress Grisel Toledo also played Nurse Tyra in "Happily Ever After".