James Ford is one of the main protagonists of Lost, and thus his family is central to the series and its stories.
- James Ford - A highly skilled conman that went to Australia to find the man responsible for his parents deaths, but ended up killing the wrong man. When going back to Los Angeles, his plane crashed.
- Warren Ford - James's father that shot himself in the head, right above his son.
- Mary Ford - James's mother that was shot by her husband, just a few meters away from their son.
- Clementine Phillips - James's daughter whom he abandoned with the mother
- Doug - James's uncle who possibly died of a brain tumor.
- Cassidy Phillips - James's former lover and con victim whom he got pregnant.
- Juliet Burke - James's fiance-to-be who died in his arms.
- Kate Austen - James's past romance whom he met on The Island.
Note: Juliet's family, Claire's family and Kate's family intertwine with Sawyer's.