"Mother of a Plan" is an orchestral piece from the Season 6 soundtrack.
She recites an incantation over a wine bottle and urges Jacob to drink it. He realizes he is her second choice, after his brother; but she convinces him that he is the correct choice - and that the choice isn't his. He drinks and becomes the protector.
The next day, his brother wakes and finds his well filled. He then sees smoke in the distance and runs to his village. The huts are on fire and all are dead. He finds his senet box and wails; and after a few seconds, the sorrow becomes rage.