On the Island
Days 54-67 (Season 2)
Days 69-90 (Season 3)
With the assistance of Jason, he administered an injection into Sawyer's chest in the Hydra operation room. Later, he and Jason accompanied Ben and Sawyer on their journey to the Hydra Island Lookout. ("Every Man for Himself")
- Matthew was killed in the beach raid by Jin along with Luke. Matthew and Luke are the names of the ones who wrote of two self-named the Gospels in The New Testament of the Bible.